Corrected Sodium Formula:
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The corrected sodium formula accounts for the dilutional effect of hyperglycemia on serum sodium levels. It provides a more accurate assessment of sodium concentration in patients with elevated blood glucose levels.
The calculator uses the MDCalc formula:
Where:
Explanation: For every 100 mg/dL increase in glucose above 100 mg/dL, serum sodium decreases by approximately 1.6 mEq/L due to osmotic fluid shifts.
Details: Correcting sodium for hyperglycemia is crucial for accurate diagnosis and management of electrolyte disorders, particularly in diabetic patients.
Tips: Enter measured sodium in mEq/L and glucose in mg/dL. Both values must be positive numbers.
Q1: Why is sodium correction necessary?
A: High glucose levels cause water to shift from cells to extracellular space, diluting sodium. Correction gives the "true" sodium concentration.
Q2: What is the normal range for corrected sodium?
A: Normal range is 135-145 mEq/L, same as uncorrected sodium. The formula just accounts for glucose's dilutional effect.
Q3: When should I use this correction?
A: Use when glucose is >100 mg/dL. The effect becomes clinically significant at glucose >200 mg/dL.
Q4: Are there alternative correction factors?
A: Some sources use 2.4 instead of 1.6, but 1.6 is more widely accepted and evidence-based.
Q5: Does this apply to all hyperglycemic states?
A: The formula works best for hyperglycemia due to diabetes. Other causes may have different relationships.