Corrected Sodium Formula:
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The corrected sodium formula adjusts serum sodium levels in the presence of hyperglycemia. It provides a more accurate assessment of sodium concentration by accounting for the osmotic shift of water caused by elevated glucose levels.
The calculator uses the corrected sodium formula:
Where:
Explanation: The equation accounts for the dilutional effect of hyperglycemia on serum sodium levels, with a correction factor specific to women.
Details: Accurate sodium correction is crucial for proper diagnosis and management of electrolyte imbalances in patients with hyperglycemia, particularly in diabetic emergencies.
Tips: Enter serum sodium in mEq/L and glucose in mg/dL. Both values must be positive numbers for accurate calculation.
Q1: Why is sodium correction needed?
A: Hyperglycemia causes water to shift from intracellular to extracellular space, diluting sodium concentration. Correction provides the "true" sodium level.
Q2: Is the correction factor different for men?
A: Yes, the correction factor is typically 2.4 for men rather than 1.6 for women.
Q3: What glucose level requires correction?
A: Correction is generally needed when glucose exceeds 100 mg/dL, though clinically significant effects are usually seen above 200 mg/dL.
Q4: Are there limitations to this formula?
A: This is an estimate. Other factors like urea, mannitol, or severe hypertriglyceridemia can also affect sodium measurements.
Q5: How does this affect treatment decisions?
A: Corrected sodium helps guide fluid replacement therapy and prevents inappropriate treatment of pseudohyponatremia.